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Annoroad Gene Technology Co Ltd cell transcriptome sequencing analysis
Cell Transcriptome Sequencing Analysis, supplied by Annoroad Gene Technology Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cell+transcriptome+sequencing+analysis/analysis+cell+sequencing+transcriptome/pm41420899-184-21-18
Average 86 stars, based on 1 article reviews
cell transcriptome sequencing analysis - by Bioz Stars, 2026-09
86/100 stars

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Single Cell:

Article Title: Rap1b is a critical regulator of germinal vesicle breakdown in porcine oocytes.
Article Snippet: Germinal vesicle breakdown (GVBD) is a pivotal event in oocyte nuclear maturation, yet its underlying molecular mechanisms remain incompletely elucidated.. This study showed that GVBD initiation in porcine oocytes occurred at 19 h of in vitro maturation, and this process was characterized by a significant increase in lamin A/C phosphorylation, prominent spindle assembly, and marked phosphorylation coupled with nuclear translocation of p38α MAPK (P < 0.05).. Inhibition of p38 MAPK with SB203580 substantially suppressed p-p38α MAPK level, resulting in a significant decrease in GVBD rate, accompanied by notably diminished p-lamin A/C and impaired spindle assembly (P < 0.05).

Sequencing:

Article Title: Rap1b is a critical regulator of germinal vesicle breakdown in porcine oocytes.
Article Snippet: Germinal vesicle breakdown (GVBD) is a pivotal event in oocyte nuclear maturation, yet its underlying molecular mechanisms remain incompletely elucidated.. This study showed that GVBD initiation in porcine oocytes occurred at 19 h of in vitro maturation, and this process was characterized by a significant increase in lamin A/C phosphorylation, prominent spindle assembly, and marked phosphorylation coupled with nuclear translocation of p38α MAPK (P < 0.05).. Inhibition of p38 MAPK with SB203580 substantially suppressed p-p38α MAPK level, resulting in a significant decrease in GVBD rate, accompanied by notably diminished p-lamin A/C and impaired spindle assembly (P < 0.05).



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